One patient required systemic cyclosporine, but only of low dose (25 mg/day). The symptoms of 17 patients were well-controlled, requiring only topical treatment and/or oral antihistamines. The duration of AIT ranged from 2 to 58 months. Seven patients were not sensitized to HDMs and only sensitized to cat and/or dog dander. Only two patients had AD only, and the other 17 patients had one or more concomitant allergic diseases, such as allergic rhinitis, allergic asthma, or allergic conjunctivitis. The patients consisted of 4 males and 15 females with an average age of 31.74 ± 9.71. ResultsĪ total of 19 patients with AD underwent AIT using cat and/or dog dander. Also, the specific IgE levels and IgG4 levels were measured before and after AIT. Patients’ medical information was obtained, including past treatment history, treatment duration of AIT, and the progress of treatment. This study enrolled patients with AD who were sensitized to cat and/or dog dander and underwent AIT (n = 19). For patients sensitized to animal (dog or cat) dander, the treatment may not be easy, especially when avoiding the allergen is not possible. Of the several treatment options available, allergen-specific immunotherapy (AIT) has been recognized as an effective treatment modality that is directed toward the immunoglobulin E (IgE)-mediated nature of AD, and subcutaneous administration using HDM is most commonly used for AIT in AD.
#Cuesta aa library science online skin#
Atopic dermatitis (AD) is a chronic inflammatory skin disease, and AD patients are commonly sensitized to house dust mite (HDM).